Weekend Trips from Ocean Isle Beach, NC

Ocean Isle Beach, North Carolina, offers a beautiful blend of relaxation, charm, and coastal living. Residents and visitors alike love its pristine beaches, family-friendly vibe, and laid-back pace. Yet one of the many advantages of living in Ocean Isle Beach is its prime location.

Nestled between Myrtle Beach, South Carolina, and Wilmington, North Carolina, it serves as a perfect home base for exciting weekend getaways. Whether you crave bustling city attractions, historic charm, or quiet natural escapes, there are countless destinations within just a few hours’ drive.

Here are some of the best weekend trips you can take from Ocean Isle Beach, each offering something special to explore.

Only about 45 minutes south, Myrtle Beach is one of the most convenient and action-packed weekend trips. Known for its vibrant entertainment, it’s a destination where you can easily pack your days with activities.

Spend your time strolling along the iconic Myrtle Beach Boardwalk, complete with shops, restaurants, and attractions like the SkyWheel, which offers breathtaking views of the coastline. Golfers will find paradise here with dozens of world-class golf courses nearby. For family fun, Myrtle Beach has waterparks, mini golf, and live shows, ensuring entertainment for all ages.

Evenings in Myrtle Beach are just as lively. Broadway at the Beach is a hotspot featuring dining, nightlife, and theaters, while Barefoot Landing offers a mix of boutiques and waterfront eateries. Whether you want a high-energy weekend or a family-focused adventure, Myrtle Beach is just a short drive from home.

Heading north for about an hour brings you to Wilmington, a historic port city brimming with Southern charm. With its cobblestone streets, riverfront views, and cultural attractions, Wilmington makes for an ideal blend of history and modern appeal.

Start your trip along the scenic Riverwalk, lined with shops, art galleries, and excellent restaurants. History lovers will enjoy visiting the USS North Carolina Battleship Memorial, which provides a fascinating look at World War II history. Downtown Wilmington is home to craft breweries, unique boutiques, and a thriving arts scene.

Nearby beaches like Wrightsville Beach and Carolina Beach offer a different flavor of coastal living, with plenty of opportunities for surfing, paddleboarding, and fishing. Wilmington’s charm lies in its ability to offer both bustling city life and natural retreats, making it a versatile weekend getaway.

Charleston is about four hours southwest of Ocean Isle Beach for a longer trip that's well worth the drive. Known for its historic beauty, cultural depth, and incredible cuisine, Charleston offers a weekend steeped in Southern elegance.

Wander through the city’s historic district, where cobblestone streets, colorful homes, and centuries-old churches create a picturesque atmosphere. Visit plantations and gardens to soak in Charleston’s rich history and stunning landscapes. The city’s food scene is world-renowned, with everything from fresh seafood to modern Southern dishes prepared by celebrated chefs.

Charleston’s waterfront adds even more charm, whether you’re enjoying a harbor cruise or simply relaxing along the Battery promenade. For those who want a romantic or culture-filled weekend, Charleston is one of the region’s crown jewels.

About three and a half hours inland, Raleigh, the capital of North Carolina, offers an urban getaway filled with museums, parks, and modern city energy. Known as part of the Research Triangle, Raleigh blends history with innovation.

Spend time exploring the North Carolina Museum of Art, the Museum of Natural Sciences, or the North Carolina Museum of History. Outdoor enthusiasts will enjoy the city’s many greenways and parks, perfect for biking, jogging, or strolling. Downtown Raleigh has a bustling dining and nightlife scene, making evenings just as engaging as the daytime activities.

For those who enjoy shopping, Raleigh’s malls and boutique districts provide plenty of options. The city is also a hub for concerts and festivals, so a weekend trip might coincide with an exciting event. Raleigh offers a well-rounded experience with something for everyone.

If you’re craving mountain scenery, Asheville is a little farther away at about five and a half hours, but it makes for a fantastic long weekend trip. Nestled in the Blue Ridge Mountains, Asheville is famous for its artsy atmosphere, outdoor adventures, and historic landmarks.

The crown jewel of Asheville is the Biltmore Estate, America’s largest privately owned home, where you can explore the grand mansion, lush gardens, and a working winery. Downtown Asheville is alive with art galleries, street performances, and an array of locally owned restaurants and breweries.

Nature lovers will find endless opportunities here, from hiking the scenic Blue Ridge Parkway to exploring Pisgah National Forest and Great Smoky Mountains National Park. Asheville combines the beauty of the outdoors with a vibrant cultural scene, making it a destination worth the drive.

For a truly unique escape, head just under two hours north to Bald Head Island. Accessible only by ferry, this car-free island offers a tranquil retreat from the everyday hustle.

Once on the island, you’ll find sandy beaches, maritime forests, and marshes perfect for exploration. Rent a golf cart or bike to get around, and enjoy the peace that comes with an unhurried pace of life. Visit Old Baldy Lighthouse, North Carolina’s oldest standing lighthouse, or take part in kayaking and paddleboarding adventures.

Bald Head Island is perfect for a low-key weekend where relaxation and natural beauty take center stage.

At just under four hours west, Greenville has gained recognition as one of the South’s most charming up-and-coming cities. It offers a lively downtown filled with restaurants, shops, and entertainment.

Falls Park on the Reedy is a must-see, featuring stunning gardens and a suspension bridge that overlooks a waterfall right in the heart of the city. Greenville is also a hub for outdoor activities, with nearby hiking trails and access to the Blue Ridge Mountains.

The city’s arts scene, food culture, and Southern hospitality make it a wonderful spot for a weekend getaway.

One of the biggest perks of living in Ocean Isle Beach is the ability to enjoy the best of both worlds: peaceful coastal living and quick access to vibrant destinations. Whether you prefer bustling cities, historic gems, mountain adventures, or quiet islands, there’s always somewhere new to discover within a weekend’s reach.

Living in Ocean Isle Beach means you’re never far from incredible experiences. From the sandy shores outside your door to the many weekend trips within a few hours’ drive, it’s a lifestyle filled with opportunity. If you’re ready to explore homes in this beautiful coastal community, The Cheek Team is here to guide you. As Southeastern NC real estate experts, they know the ins and outs of Ocean Isle Beach and the surrounding areas.

Start your real estate journey with a trusted partner. Visit The Cheek Team today and let them help you find the perfect home base for your coastal lifestyle.